Simple ways to take the edge off the edge vial effect in freeze drying
Bart draws attention to the edge vial effect and how to reduce its negative impact during the freeze-drying process →
How to master chromatography in two days
Bart invites users to an advanced user chromatography training →
The poster that could put Bart’s Blog out of a job
Bart offers a sneak peak into a free chromatography poster with the basic principles needed to perform perfect flash chromatography and prep HPLC →
What happens if you run your freeze drying process under direct sunlight
Bart experiments with the effect of direct sunlight on freeze drying performance and draws attention to how the environment can influence lyophilization →
We need to talk about flow rate and column efficiency in chromatography
Bart discusses how an optimized flow rate helps improve the column efficiency of flash and prep HPLC chromatography →
How to find a suitable pressure endpoint criterion for freeze drying
Bart discusses comparative pressure measurement and how to use it for endpoint determination of freeze-drying steps →
Three major ways to influence column efficiency in your favor
Bart explains how particle size, column packing and pore size affect column efficiency and resolution in chromatography →
How to use temperature to assess if primary freeze drying is finished
Bart describes how temperature could be used for endpoint determination of the primary drying step in lyophilization →
Why you should care about column efficiency
Bart explains how column efficiency, or the number of theoretical plates, affect resolution in chromatography →
Why pressure gradients are the main drivers in improving sublimation rates
Bart discusses why a good pressure gradient is the most efficient way to improve freeze-drying rates →
Putting safety first during the chromatography process
Bart discusses how to maximize the safety of user, sample and the surroundings during the chromatography process →