moisture mapping, freeze drying, lyophilization, moisture content, freeze dried product

Why a bit of moisture in freeze-dried products can be a good thing

Bart discusses the danger of overdrying during the freeze-drying process and how moisture mapping can help achieve optimal moisture content in products →

column efficiency, plate height, sample load, sample overload, preparative chromatography, flash chromatography, prep HPLC

Does anyone in chromatography give a load about the sample load?

Bart talks about sample overload in chromatography and how it affects plate height, column efficiency and resolution →

freeze drying, condenser overload, freeze drying unit, freeze drying process, freeze drying rate, condenser ice capacity

A load of tips on how to prevent condenser overload

Bart describes how freeze-driyng rates, condenser ice capacity and other parameters can be used to prevent condenser overload →

chromatography webinar, preparative chromatography, flash chromatography, chromatography questions

Five good reasons to attend my live Q&A chromatography webinar

Bart invites readers of his blog to join a live Q&A chromatography webinar where he personally answers their purification questions →

edge vial, edge vial effect, ferrule, metallic ring, lyophilization, freeze drying

Simple ways to take the edge off the edge vial effect in freeze drying

Bart draws attention to the edge vial effect and how to reduce its negative impact during the freeze-drying process →

BUCHI, flash chromatography, prep HPLC, preparative chromatography, chromatography training, advanced chromatography

How to master chromatography in two days

Bart invites users to an advanced user chromatography training →

chromatography principles, chromatography basics, flash chromatography, prep HPLC, chromatography method, chromatography method development

The poster that could put Bart’s Blog out of a job

Bart offers a sneak peak into a free chromatography poster with the basic principles needed to perform perfect flash chromatography and prep HPLC →

freeze drying, lyophilization, environment, sunlight

What happens if you run your freeze drying process under direct sunlight

Bart experiments with the effect of direct sunlight on freeze drying performance and draws attention to how the environment can influence lyophilization →

column efficiency, flow rate, chromatography

We need to talk about flow rate and column efficiency in chromatography

Bart discusses how an optimized flow rate helps improve the column efficiency of flash and prep HPLC chromatography →

endpoint criterion, freeze drying, lyophilization, comparative pressure measurement, mamometer, priani gauge

How to find a suitable pressure endpoint criterion for freeze drying

Bart discusses comparative pressure measurement and how to use it for endpoint determination of freeze-drying steps →

column efficiency, number of theoretical plates, particle size, particle diameter

Three major ways to influence column efficiency in your favor

Bart explains how particle size, column packing and pore size affect column efficiency and resolution in chromatography →